Table 1.
Characteristics of participants included in the analysis of the effects of aspirin and UGT1A6 genotype on gene expression in colonic epithelium and stroma
| UGT1A6*1/*1 | UGT1A6*2/*2 | |||
|---|---|---|---|---|
| Men n = 9 | Women n = 11 | Men n = 9 | Women n = 13 | |
| Age, years (SD) | 30.0 (4.65) | 30.9 (5.8) | 30.2 (5.6) | 29.7 (7.8) |
| Height, cm (SD) | 180.9 (5.6) | 168.5 (7.2) | 179.0 (7.8) | 163.2 (8.0) |
| Weight, kg (SD) | 83.6 (8.4) | 69.0 (12.0) | 88.2 (26.5) | 71.3 (15.5) |
| BMI, kg/m2 (SD) | 25.6 (2.6) | 24.2 (3.2) | 27.5 (7.8) | 26.7 (5.2) |
| Minority, n (%) | 2 (22.2) | 3 (27.3) | 3 (33.3) | 2 (15.4) |
| Race n (%) | ||||
| Caucasian | 6 (66.7) | 6 (54.6) | 6 (66.7) | 11 (84.6) |
| Asian | 1 (11.1) | 1 (9.1) | 2 (22.2) | 1 (7.7) |
| African-American | 0 | 1 (9.1) | 0 | 0 |
| Other | 2 (22.2) | 3 (27.2) | 1 (11.1) | 1 (7.7) |
| Family history of CRC, n (%) | 0 (0.0) | 1 (9.1) | 1 (11.1) | 0 (0.0) |
| Take supplements, n (%) | 3 (33.3) | 2 (18.2) | 4 (44.4) | 6 (46.2) |
| Ever smoked n (%) | 1 (11.1) | 3 (27.3) | 1 (11.1) | 1 (7.7) |
| Energy, kcal/d (SD) | 1495 (373) | 1468 (474) | 1770 (459) | 1505 (361) |
| Fruit, servings/d (SD) | 1.3 (1.0) | 1.9 (0.9) | 2.5 (1.8) | 2.9 (2.3) |
| Vegetables, servings/d (SD) | 1.5 (1.2) | 2.3 (1.2) | 1.7 (1.0) | 2.6 (2.1) |
| Caffeine mg/d (SD) | 68 (92) | 76 (60) | 125 (147) | 118 (71) |
| Calcium mg/d (SD) | 926 (508) | 760 (373) | 782 (267) | 773 (406) |
| Fat g/d (SD) | 57 (20) | 56 (20) | 67 (29) | 46 (20) |
| Dietary fiber, g/d | 15.9 (8.3) | 15.5 (5.6) | 19.2 (9.0) | 20.4 (8.4) |
Abbreviations: CRC, colorectal cancer; SD, standard deviation.
Asterisks are used as part of the specific classification of the UGT1A6 genotype.