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The endogenous levels of let-7b (A), KRAS mRNA (B) and KRAS protein (C) in NIH-H1975, A549, BxPC-3 and Panc-1 cells. The expression of let-7b (D), KRAS protein (E) and KRAS mRNA (F) in the cells transfected with let-7b mimic alone or in combination with PTX or GEM. Each experiment was carried out at least 3 times. Data represent the mean ±SEM. *, p < 0.05; **, p < 0.01.
