Table 3. Thermodynamic Parameters between bufadienolides-HSA interaction at pH 7.4.
| Compounds | T(K) | ΔG (kJ·mol-1) | ΔH (kJ·mol-1) | ΔS (J·mol-1·K-1) |
|---|---|---|---|---|
| 298 | -27.82 ± 2.63 | |||
| gamabufotalin | 302 | -27.46 ± 2.83 | -54.91 ± 9.58 | -90.89 ± 0.48 |
| 310 | -26.47 ± 3.11 | |||
| 298 | -27.48 ± 3.37 | |||
| arenobufagin | 302 | -26.46 ± 1.40 | -254.56 ± 41.78 | -103.33 ± 1.27 |
| 310 | -25.96 ±0.76 | |||
| 298 | -26.74 ± 1.02 | |||
| cinobufagin | 302 | -26.02 ±1.57 | -80.32 ± 12.61 | -179.81 ± 1.49 |
| 310 | -25.38 ±2.30 | |||
| 298 | -25.66 ± 0.91 | |||
| bufotalin | 302 | -24.91 ±0.42 | -81.97 ± 28.01 | -188.94 ± 1.96 |
| 310 | -24.45 ±1.98 | |||
| 298 | -24.72 ± 1.48 | |||
| hellebrigenin | 302 | -24.02 ±1.06 | -76.85 ± 3.16 | -192.13 ± 2.59 |
| 310 | -24.01 ±0.25 | |||
| 298 | -24.64 ± 1.07 | |||
| telocinobufagin | 302 | -24.81 ±1.91 | -42.25 ± 17.66 | -59.11 ± 0.67 |
| 310 | -24.16 ±1.47 | |||
| 298 | -24.48 ± 0.30 | |||
| resibufogenin | 302 | -23.81 ±0.48 | -29.74 ± 17.02 | -17.67 ± 1.19 |
| 310 | -23.61 ±0.63 | |||
| 298 | -24.08 ± 0.88 | |||
| bufalin | 302 | -23.79 ±0.34 | -45.72 ± 1.79 | -72.59 ± 0.88 |
| 310 | -23.68 ±1.01 | |||
| 298 | -22.86 ± 0.51 | |||
| desacety-bufotalin | 302 | -22.59 ±0.67 | -42.80 ± 6.27 | -66.91 ± 0.10 |
| 310 | -22.00 ±2.83 |