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. 2015 Apr 30;12:39. doi: 10.1186/s12977-015-0167-3

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© Serrao et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Sequence logos for PFV and HIV-1 integration sites in nucleosome-free versus chromatinized tDNA. (A) The logo illustrates the average nucleotide sequence of the first 50 nucleotides of center-aligned nucleosomal DNA sequences isolated from chicken erythrocytes [68]. (B) PFV integration sites derived from virus-infected cells [92,93]. (C) Integration sites from recombinant PFV intasomes and deproteinized cellular DNA. (D) HIV-1 integration sites from virus-infected cells [87]. (E) Concerted HIV-1 integration sites from recombinant HIV-1 IN and naked pGEM9Zf(−) plasmid DNA [33].