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. 2015 Apr 30;15:66. doi: 10.1186/s12871-015-0049-1

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© Liu et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative I_Ca traces obtained from ventricular myocytes groups: control, bupivacaine 100 μmol/L alone, and bupivacaine 100 μmol/L in combination with epinephrine 0.15 μg/ml. Family of current traces obtained by applying a series of 250 ms pulses ranging from -40 mV to 50 mV with a holding potential of -40 mV.