Table 1.
Variable overview
| Study visit | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Time point test | <7 d of first ECT | 1– 2 h before first ECT | 1– 2 h after first ECT | 7 – 14 d after last ECT | 6 mo after ECT-series | |
| Informed consent | X | |||||
| Diagnostic interview | MINI plus | X | ||||
| Clinical assessment | Clinical examination | X | ||||
| Illness history, previous episodes and ECT-treatment | X | |||||
| Current and concomitant medication | X | X | X | |||
| Symptom severity | MADRS | X | X | X | ||
| CGI | X | X | X | |||
| Relapse | Interview | X | ||||
| Overall cognitive function | MMS | X | X | X | ||
| Neuropsychological assessment | WASI | X | X | |||
| CVLT-II, Rey, Digit span from WASI-R, WCST, D-kefs: Color-Word interference test, Word fluency, Tower, TMT, CPT, Digit symbol WAIS-R, Pegboard | X | X | X | |||
| Autobiographical memory | AMI-SF | X | X | X | ||
| Everyday memory | EMQ | X | X | X | ||
| Cognitive control | Dichotic listening | X | X | X | ||
| Blood samples | Full blood, EDTA and PAX-gen for biobank | X1) | X1) | X1) | X2) | |
| Radiology | MRI caput; T1 FSPGR, T2 CUBE FLAIR, RSI, SWI, MRS, MEGAPRESS | X | X | X | X |
1)Before MRI.
2)Before and after MRI.