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. 2015 May 6;10(5):e0125943. doi: 10.1371/journal.pone.0125943

Table 2. Comparison of signal, noise, SNR and CNR between the reconstructions FBP/QDS, AIDR 3D mild, AIDR 3D standard and AIDR 3D strong.

ANOVA t-test
  FBP/QDS   MILD   STD   STR   p p1 p2 p3 p4 p5 p6
Signal 155.3 (53.7) 155.0 (53.5) 152.5 (53.4) 149.9 (53.3) <0.001 1.000 <0.001 <0.001 <0.001 <0.001 <0.001
Noise 32.8 (9.3) 34.5 (8.9) 29.8 (8.3) 27.0 (7.8) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
SNR 10.4 (3.0) 9.4 (3.0) 11.1 (3.7) 12.6 (4.4) <0.001 0.001 0.001 <0.001 <0.001 <0.001 <0.001
CNR 12.5 (4.3) 11.4 (3.1) 13.5 (3.9) 15.3 (4.7) <0.001 0.002 <0.001 <0.001 <0.001 <0.001 <0.001

Values are given in arithmetic mean (SD); reconstruction with filtered back projection/ quantum denoising filtering system (FBP/QDS), adaptive iterative dose reduction (AIDR) 3D mild (MILD), standard (STD) and strong (STR); The values of all measurement points are summarised; First, Repeated Measures ANOVA overall analysis including every measurement point as dependent variable showed p<0.001 (p ANOVA) for signal, noise, SNR and also CNR. Subsequently, t-test was used as single test for the 4 quantitative parameters. Bonferroni correction was automatically performed for the multiple testing with 6 possibilities: p1 (FBP/QDS-AIDR 3D mild), p2 (FBP/QDS-AIDR 3D standard), p3 (FBP/QDS-AIDR 3D strong), p4 (AIDR 3D mild-AIDR 3D standard), p5 (AIDR 3D mild-AIDR 3D strong), p6 (AIDR 3D standard-AIDR 3D strong); signal presents the density in Hounsfield Units; noise is SD of the signal; SNR = signal in the vessel measurement point/noise in the aorta ascendens measurement point; CNR = (signal in the surrounding tissue of the vessel measurement point—signal in the vessel measurement point)/noise in the aorta ascendens measurement point.