Table 3. Age and hematological parameters according clinical phenotypes of the study population.
| variables | ACP n = 43 | MCP n = 115 | SCP n = 53 | p* (anova) |
|---|---|---|---|---|
| Age (years) | 25.9±10.0 | 20.5±11.2 | 18.9±9.1 | 0.003 |
| Hemoglobin (g/dl) | 9.1±1.7 | 7.5±1.3 | 6.8±1.6 | 0.001 |
| Hb F (%) | 15.7±7.4 | 4.6±2.9 | 0.0 | 0.001 |
| Hematocrit | 28±5 | 23±4 | 21±5 | 0.001 |
| RBCs(x 10 6 /μL) | 3.7±0.9 | 3.0±0.7 | 2.6±0.7 | 0.001 |
| WBCs(x10 3 /μL) | 8.9±4.1 | 13.0±6.3 | 15.0±6.0 | 0.001 |
| Reticulocytes (%) | 11.3±9.1 | 16.2±10.3 | 17.6±11.3 | 0.009 |
| Platelets (x10 3 /μL) | 249.1±104.4 | 288.4±157.4 | 349.1±236.9 | 0.02 |
| MCV (fl) | 79±12 | 79±10 | 84±12 | 0.01 |
| MCHC (g/dL) | 33±1 | 33±2 | 33±2 | 0.96 |
| LDH (U/I) | 705±299 | 840±294 | 897±274 | 0.01 |
*Anova test;
ACP: Asymptomatic clinic phenotype; MCP: Moderate clinic phenotype; SCP: Severe clinic phenotype; HbF: Fetal hemoglobin; RBCs: Red Blood Cells; WBCs: White Blood Cells; MCV: Mean corpuscular volume; MCHC: Mean corpuscular hemoglobin concentration; LDH: Lactodehydrogenase