. 2015 May 6;10(5):e0122283. doi: 10.1371/journal.pone.0122283

Table 8. CPM Additions of Substitutions And Associated β-lactam Antibiotics From Optimal Six Step Treatment Plans (*Maximum Probability for Path).

Substitutions	Drugs associated with substitutions in optimal paths (probability)
0000–1000	CTT(0.38*)
0000–0100
0000–0010
0000–0001
1000–1100
1000–1010
1000–1001
0100–1100	SAM(1.0*)
0100–0110	CTX(1.0), CPD(1.0)
0100–0101
0010–1010	CTT(0.22)
0010–0110
0010–0011
0001–1001	AM(1.0), CTT(0.47), SAM(1.0)
0001–0101
0001–0011
1100–1110	CAZ(0.85*), SAM(0.046), FEP(0.32)
1100–1101	AMP(1.0*),CAZ(0.15), SAM(0.95), FEP(0.68)
1010–1110	CEC(1.0*), CTT(0.47)
1010–1011
1001–1101
1001–1011	CTX(0.50*)
0110–1110	FEP(1.0*)
0110–0111	ZOX(1.0), CXM(0.94), CPD(1.0)
0101–1101	AMP(1.0), FEP(1.0)
0101–0111	CTX(0.58), ZOX(1.0*), CXM(0.59), CPD(0.85)
0011–1011	CTT(0.04)
0011–0111	ZOX(1.0), CPD(1.0)
1110–1111	AM(0.90), CRO(0.53), SAM(1.0*), CPD(0.39), FEP(0.72)
1101–1111	AMP(1.0), SAM(1.0), FEP(1.0*)
1011–1111	TZP(0.03)
0111–1111	CPD(1.0*)