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. 2015 May 6;10(5):e0122283. doi: 10.1371/journal.pone.0122283

Table 10. EPM Additions of Substitutions and Associated β-lactam Antibiotics From Optimal Six Step Treatment Plans (*Maximum Probability for Path).

Mutations β-lactams associated with substitutions in optimal paths (probability)
0000–1000
0000–0100
0000–0010
0000–0001
1000–1100
1000–1010
1000–1001
0100–1100 SAM(1.0*)
0100–0110
0100–0101 TZP(1.0*)
0010–1010
0010–0110
0010–0011
0001–1001 AM(1.0*), SAM(1.0*)
0001–0101 TZP(1.0*)
0001–0011
1100–1110 CTT(1/4)
1100–1101 AMP(1.0*), CPR(1/4)
1010–1110 CTT(1/2)
1010–1011
1001–1101
1001–1011 CTX(1/2*)
0110–1110 CTT(1/3)
0110–0111
0101–1101 AM(1/2), AMC(1/2)
0101–0111
0011–1011 AMC(1/2*)
0011–0111
1110–1111 SAM(1.0*)
1101–1111
1011–1111 CTT(1/3)
0111–1111 SAM(1/2), CPD(1.0*)