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. 2015 May 6;10(5):e0125169. doi: 10.1371/journal.pone.0125169

Fig 3. Effect of APN on TGF-β1, CTGF and α-SMA expression in lung tissues from control animals or PQ-exposed animals, treated with vehicle or APN. PQ (10 mg/kg, IP) increased, whereas APN (100 μg/kg or 500μg/kg, IV) revised, TGF-β1 (A), CTGF (B) and α-SMA (C) expression in mice lung tissues at 3, 14 and 21 d after PQ injection.

Fig 3

The protein and mRNA expression were a determined via Western blot and RT-PCR, respectively. Values represent the mean ± standard error of the mean of four parallel measurements. *P<0.05. APN, adiponectin; TGF-β1, transforming growth factor-β1; CTGF, connective tissue growth factor; α-SMA, α-smooth muscle actin; PQ, paraquat.