Fig 2. Effect of compound (1) and (2) on cell growth and cellular morphology.
Cells were treated with 50 μM (1) or (2) or DMSO alone and images were captured using a live cell image analyzer JuliBr system for 24 hours. (A) Cell confluency was determined every hour. Addition of compound (1) or (2) lead to decreased cell confluency of both breast cancer cell-lines (MCF-7 or MDA-MB-231) and human normal breast epithelial cell-line (MCF-10A) compared to untreated control (B) Cell shrinkage and formation of apoptotic bodies were observed in (left) MCF-7 or (right) MDA-MB-231 cells after 24 hours treatment with (1) or (2).