Table 4. Top Differentially Expressed Genes Post-transplant Following Kidney Transplant compared to baseline with FDR < 0.01 and 2 or greater fold change.

Week 1			Month 3			Month 6
Gene ID	Entrez gene name	Fold change	Gene ID	Entrez gene name	Fold change	Gene ID	Entrez gene name	Fold change
Higher Levels Than at Baseline
TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like	18.20	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like	10.64	OSBPL9	oxysterol binding protein-like 9	4.63
TMEM205	transmembrane protein 205	14.37	TMEM205	transmembrane protein 205	6.48	CD300LD	CD300 molecule-like family member d	4.22
OLFM4	olfactomedin 4	10.73	OSBPL9	oxysterol binding protein-like 9	6.38	HBB	hemoglobin, beta	4.09
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	9.24	UBXN11	UBX domain protein 11	5.36	NREP	neuronal regeneration related protein	3.91
OSBPL9	oxysterol binding protein-like 9	8.55	MMP8	matrix metallopeptidase 8	4.69	HBA2	hemoglobin, alpha 1	3.90
LTF	Lactotransferrin	7.93	NREP	neuronal regeneration related protein	4.60	BMP6	bone morphogenetic protein 6	3.82
AZU1	azurocidin 1	7.88	CD177	CD177 molecule	4.20	HBA1	hemoglobin, alpha 1	3.82
CRISP3	cysteine-rich secretory protein 1	7.85	OLFM4	olfactomedin 4	3.95	MNF1	Ubiquinol-cytochorome C reductase complex assembly factor 2	3.71
BPI	bactericidal/permeability-increasing protein	7.73	HP	haptoglobin	3.87	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)	3.20
UBXN11	UBX domain protein 11	7.58	CRISP3	cysteine-rich secretory protein 1	3.80	SYVN1	synovial apoptosis inhibitor 1, synoviolin	3.15
Lower Levels than at Baseline
IL7R	interleukin 7 receptor	-17.73	C1orf204	chromosome 1 open reading frame 204	-14.13	ELK2AP	ELK2A, member of ETS oncogene family, pseudogene	-12.25
KLRC3	killer cell lectin-like receptor subfamily C, member 3	-16.61	VSIG8	V-set and immunoglobulin domain containing 8	-14.13	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	-11.41
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	-14.99	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	-7.67	C1orf204	chromosome 1 open reading frame 204	-10.21
CD3D	CD3d molecule, delta (CD3-TCR complex)	-14.39	C10orf105	chromosome 10 open reading frame 105	-5.37	VSIG8	V-set and immunoglobulin domain containing 8	-10.21
KLRC2	killer cell lectin-like receptor subfamily C, member 2	-14.27	IL7R	interleukin 7 receptor	-5.29	STAG3	stromal antigen 3	-6.49
KLRB1	killer cell lectin-like receptor subfamily B, member 1	-13.78	LEF1	lymphoid enhancer-binding factor 1	-5.16	MIR650	microRNA 650	-5.38
KLRC1	killer cell lectin-like receptor subfamily C, member 1	-13.51	MAL	mal, T-cell differentiation protein	-4.94	C10orf105	chromosome 10 open reading frame 105	-4.93
CD3G	CD3g molecule, gamma (CD3-TCR complex)	-11.94	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	-4.65	EPHB1	EPH receptor B1	-4.87
LEF1	lymphoid enhancer-binding factor 1	-11.71	TCF7	transcription factor 7 (T-cell specific, HMG-box)	-4.60	IGLL5	immunoglobulin lambda-like polypeptide 1	-4.81
ITK	IL2-inducible T-cell kinase	-10.82	CD3D	CD3d molecule, delta (CD3-TCR complex)	-4.60	IL8	chemokine,ligand 8	-4.31