Table 3.
25(OH)D and Incident Traumatic and Non-Traumatic Fracture Over the Menopausal Transition
| Fractures | Base Model, HR (95% CI)a | Multivariate Model, HR (95% CI)b |
|---|---|---|
| Traumatic fractures | ||
| Per 10 ng/mL increase | 1.14 (0.94–1.37) | 1.02 (0.80–1.28) |
| ≥20 vs <20 ng/mL | 1.24 (0.83–1.87) | 1.11 (0.70–1.77) |
| Non-traumatic fractures | ||
| Per 10 ng/mL increase | 0.75 (0.58–0.96) | 0.72 (0.54–0.96) |
| ≥20 vs <20 ng/mL | 0.55 (0.35–0.86) | 0.54 (0.32–0.89) |
Abbreviation: 95% CI, 95% confidence interval.
a
Adjusted for age, site, and race.
b
Base model + fracture history, prior and current menopausal hormone therapy, BMI, physical activity, SF-36 Role–physical functioning score, education, lumbar spine BMD, calcium and vitamin D supplements, corticosteroids, diabetes, and dietary calcium.