Figure 6.

The effect of erlotinib and amiloride treatment on the EGFR signaling pathway in Bxpc-3 and PANC-1 cells. Cells were treated with erlotinib (10 μmol/L), amiloride (100 μmol/L), or their combination for 12 h and then harvested for western blot analysis (A). The experiment was independently repeated three times and representative results are shown in graphs (B) . Mean±SD. n=3. ^bP<0.05, ^cP<0.01 compared with control. ^eP<0.05, ^fP<0.01 compared with groups treated with erlotinib alone.