Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May;30(3):224–231. doi: 10.1152/physiol.00021.2014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©2015 Int. Union Physiol. Sci./Am. Physiol. Soc.

PMC Copyright notice

FIGURE 1. — Decreased uteroplacental perfusion in Japanese macaques fed a high-fat diet

Maternal high-fat diet (HFD) leads to increased uterine artery pulsatility Index (PI). A: uterine artery (Uta) PI is 0.74 in a representative control animal. B: the Uta PI is 1.17 in a representative HFD-sensitive (HFD-S) animal with a Doppler waveform that demonstrates decreased diastolic flow consistent with increased vascular impedance compared with A. C: the calculated Uta blood flow (cQUta) normalized to maternal weight was significantly reduced in HFD-R and HFD-S animals compared with CTR. D: Uta PI is increased in HFD-S animals compared with CTR. As a group, HFD (HFD-R + HFD-S) had a significant increase in Uta PI compared with CTR. E: the calculated umbilical vein blood flow (cQUV) normalized to fetal abdominal circumference was reduced in HFD-S animals compared with controls. There was no difference in HFD-R animals compared with controls. F: the umbilical artery (UA) PI was unaffected by diet group. *Significant difference (P < 0.0): CTR, n = 9; HFD-R, n = 6; HFD-S, n = 9. Reproduced from Ref. 13 with permission.