Figure 8.

Change in 3D binding strength upon binding to other filopodia. (A) Lateral components of stiffness parameter κ(t) during the approach to the cell body. The parameters for minimal, κ_min(t), and maximal, κ_max(t), lateral stiffness are shown by the brown and black curves, respectively. (B and C) DIC microscopy images illustrate the bead position (blue circle) relative to the cell body and other filopodia (green lines) at time points indicated by arrows in (A), revealing strong changes in the maximal stiffness, κ_max. To see this figure in color, go online.