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. 2015 Mar 10;25(5):561–573. doi: 10.1038/cr.2015.30

Figure 2.

Figure 2

Expression of FBW7 inversely correlates with ERK activation. (A) Representative IHC staining of FBW7 and p-ERK in pancreatic adenocarcinoma tissue arrays (scale bar, 200 μm; inset scale bar, 40 μm). (B) Statistical analysis of the correlation between the levels of FBW7 and p-ERK (P = 0.027; P value was obtained using a Pearson χ2 test). (C) Representative IHC staining of Fbw7 and p-Erk in KrasG12D transgenic mice. Control slides were obtained from the same mouse strain, which was kept in the same conditions and sacrificed at the same age as the transgenic mice (scale bar, 100 μm).