Table 3.
Correlation of Aurora-A expression with histological and clinical responses to CRT in the surgical group of ESCC patients
| Histological response to CRT (n = 41) | |||||
|---|---|---|---|---|---|
| Grade1 | Grade2 | Grade3 | Total | P | |
| Aurora-A | |||||
| (+) | 7 | 8 | 9 | 24 | 0.003 |
| ( −) | 13 | 4 | 0 | 17 | |
| Clinical response | |||||
| CR | 0 | 1 | 8 | 9 | 0.0001 |
| IR/SD | 17 | 11 | 1 | 29 | |
| PD | 3 | 0 | 0 | 3 | |
Grade 2 or 3 was judged as effective CRT and a response of Grade 1 was judged as ineffective CRT.
CR: Complete Response, complete disappearance of the primary lesion.
IR/SD: Incomplete Response/Stable Disease of the primary lesion.
PD: Progressive Disease, progressive disease of the primary lesion.
Aurora-A (+)/(−), Aurora-A positive/negative expression.