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. 2015 Apr 29;6:6840. doi: 10.1038/ncomms7840

Figure 7. Advanced stage melanoma patients express higher levels of Id1 in the CD11B+ PBMC fraction and have elevated plasma TGFβ levels.

Figure 7

(a) qPCR analysis of ID1 (unpaired t-test, *P<0.05), (b) S100A8 (unpaired t-test, **P<0.01) and (c) S100A9 (unpaired t-test, **P<0.01) mRNA expression levels following isolation of CD11B+ PBMCs from metastatic melanoma patient blood samples (n=15) compared with healthy matched controls (n=7). (d) VEGFR1 mean fluorescence intensity levels in CD11B+CD14−HLA−CD33+ cells PBMCs from metastatic melanoma patient blood samples compared with healthy matched controls, determined by flow cytometry (unpaired t-test, ***P<0.001). (e) TGFβ plasma levels from metastatic melanoma patients compared with controls, measured by ELISA (unpaired t-test, **P<0.01).