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(a) Solubility curve for SQ641 versus the volume fraction, ϕ, of THF in a water/THF mixture. The SQ641 solubility at ϕ = 0.1 and ϕ = 0.05 are 0.13 and 0.03 mg mL–1, respectively. (b) Supersaturation of SQ641 obtained by mixing THF solutions that are saturated (■), have 20 mg mL–1 (●), or 10 mg mL–1 (□) SQ641 with water in the MIVM, at different relative flow ratios, yielding the final vol % THF noted on the axis.
