Table 2. Treatment outcomes of patients after endoscopic submucosal dissection of a gastric neoplasm.
(A) No APT group(n = 261) | (B) Single APT group(n = 58) | (C) DAPT group(n = 31) | A vs. B P value | A vs. C P value | |
Diameter of resected specimen(range, SD), mm | 34.1(6 – 95, 14.1) | 35.6(14 – 90, 15.3) | 37.6(12 – 98, 19.1) | 0.47 | 0.22 |
Diameter of resected specimen ≥ 40 mm, No. (%) | 73 (28.0) | 20 (34.5) | 11 (35.5) | 0.34 | 0.40 |
Location of resected lesion, No. | L : M : U = 93 : 100 : 68 | L : M : U = 22 : 20 : 16 | L : M : U = 6 : 16 : 9 | 0.86 | 0.17 |
Post-ESD Hb, mean(range, SD), g/dL | 12.9(6.5 – 16.6, 1.6) | 12.5(8.2 – 16.1, 2.0) | 12.1(8.6 – 14.6, 1.7) | 0.07 | < 0.01 |
Post-ESD bleeding, No. (%) | 16 (6.1) | 9 (15.5) | 11 (35.5) | 0.03 | < 0.01 |
Days after ESD of post-ESD bleeding(range, SD), days | 3.8(0 – 11, 3.6) | 7.3(0 – 16, 5.1) | 8.5(1 – 15, 5.0) | 0.06 | 0.01 |
Late-onset post-ESD bleeding (≥ 8 days)(percentage all of post-ESD bleeding), No. (%) | 3 (18.8) | 4 (44.4) | 7 (63.6) | 0.20 | 0.04 |
Blood transfusion, No. (%) | 3 (1.1) | 5 (8.6) | 6 (19.4) | < 0.01 | < 0.01 |
APT, antiplatelet therapy; DAPT, dual antiplatelet therapy; SD, standard deviation; L, lower; M, middle; U, upper; ESD, endoscopic submucosal dissection; Hb, hemoglobin.Note: Unpaired Student’s t test, Fisher’s exact test, and chi-squared test were used.Post-ESD bleeding occurred more frequently in the single APT and DAPT groups, and late-onset bleeding was significantly more common in the DAPT group. The requirement for blood transfusion was also higher in the single APT and DAPT groups. The locations of the resected lesions did not differ significantly among the groups.