Table 1. Proteins whose abundance in mouse splenocytes is dependent upon Gimap5: iTRAQ analysis comparing Gimap5WT/WT to Gimap5tm1Wlr/WT littermates.
Protein | Fold change het/wt | Biological process |
---|---|---|
Cyfip2 | 0.55 | Component of WAVE complex for assembly of F-actin complex |
Arhgdia | 0.57 | Rho protein signal transduction, regulation of protein localization |
Vasp | 0.57 | Actin cytoskeleton reorganization |
Elmo1 | 1.83 | Actin filament-based process, phagocytosis |
S100A9 | 2.12 | Actin cytoskeleton reorganization, leukocyte chemotaxis, phagocytosis |