Table 2.
Percentage of Normal and Glaucoma Eyes that Met the ISNT Rule for Retinal Nerve Fiber Layer Thickness. The ISNT rule holds when the retinal nerve fiber layer (RNFL) is thickest in the inferior quadrant, followed by superior, nasal, and then temporal quadrants. Optical coherence tomography RNFL thickness values are shown.
Quadrant | Normal (n=87) | Glaucoma (n=108) |
Mean ± SD [95% CI] (μm) | Mean ± SD [95% CI] (μm) | |
Inferior | 126.5 ± 17.1 [122.9 to 130.1] | 67.0 ± 21.9 [62.9 to 71.1] |
Superior | 117.0 ± 17.1 [113.4 to 120.6] | 71.3 ± 23.6 [66.8 to 75.8] |
Nasal | 75.9 ± 13.8 [73.0 to 78.8] | 49.9 ± 19.1 [46.3 to 53.5] |
Temporal | 69.0 ± 10.4 [66.8 to 71.3] | 52.4 ± 15.2 [49.5 to 55.3] |
ISNT rule met | 42/87 (48.3%) | 7/108 (6.5%) |
SD, standard deviation; CI, confidence interval.