Figure 1.

Growth of publicly available RNA-seq data and analysis workflow. (a) Over the past years the number of available public RNA-seq samples has increased exponentially (exponential fit r² > 0.991). (b) General overview of the steps taken to process, quality control and integrate all samples. LCL, lymphoblastoid cell line; PCA, principal component analysis. (c) Overview of the diversity of 4,978 samples used for expression clustering. Three samples having read lengths >140 (365, 452, 151 bases) are omitted from the read length plot.