Table 5.
Frequencies of B cell subsets [Median (IQR)]
| Subset | HC | HW | TB | TB + HW |
|---|---|---|---|---|
| B cell (%) | 7.1 (4.7–8.9) | 7.2 (3.5–7.7) | 6.6 (4.6–7.6) | 7.5 (5.8–8.4) |
| Naïve B cell (%) | 63.8 (42.2–78.5) | 71.9 (53.4–83.3) | 63.4 (57.0–74.8) | 78.8 (71.4–81.1) |
| Tissue-like memory B cell (%) | 5.0 (4.1–6.8) | 4.7 (3.8–6.0) | 3.8 (2.3–4.9) | 5.0 (4.2–6.1) |
| Activated memory B cell (%) | 7.8 (5.1–10.0) | 8.0 (7.3–9.0) | 7.5 (5.2–10.6) | 5.0 (4.8–8.6) |
| Resting memory B cell (%) | 46.8 (29.5–69.1) | 65.3 (43.2–70.4) | 46.0 (37.8–54.8) | 35.9 (33.6–43.4) |
| Plasma cell (%) | 44.6 (16.6–66.2) | 25.8 (18.0–48.1) | 44.3 (38.2–53.9) | 54.7 (47.8–60.2) |
IQR: interquartile range; HC: healthy controls without PTB or hookworm infection; HW: patients only with hookworm infection; TB: PTB cases without hookworm infection; TB + HW: PTB cases co-infected with hookworm.