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. 2015 Apr 28;9:2399–2407. doi: 10.2147/DDDT.S76602

Figure 4.

Figure 4

The effect of PP on the colony formation and gene expression of PC9, SPC-A1, and A549 cells.

Notes: (A) PP significantly decreased the colony formation in PC9, SPC-A1, and A549 cells. Quantitative polymerase chain reaction results showed the gene expression pattern of pluripotent stem cell markers and Wnt signaling components in three cell lines. Relative gene expression of (B) cells collected at D7 of colony formation, (C) SPC-A1 cells with or without PP incubation, (D) PC9 cells with or without PP incubation, and (E) A549 cells with or without PP incubation. *P<0.05, **P<0.01, and ***P<0.001 represent the colony formation or relative gene expression in D7-colony or D7-PP group compared to in the parent group.

Abbreviations: D, day; PP, pyrvinium pamoate.