Table 1. Treatment response in patients who showed a decrease or increase in pre-treatment depression stability (PT-HRSD) and slope estimates for the within condition effect of PT-HRSD on changes in depressive symptoms throughout treatment.
| Treatment | Responders (%) | Remitters (%) | Slope estimation for the within condition effect | ||||||
|---|---|---|---|---|---|---|---|---|---|
| PT-HRSD<0 | PT-HRSD≥0 | PT-HRSD<0 | PT-HRSD≥0 | Values of PT-HRSD | Slope Estimate | S.E. | z Value | p | |
| MED (n=55) | 34.48 | 26.92 | 31.03 | 19.23 | mean PT-HRSD | -2.748 | 0.266 | -10.30 | <.0001 |
| mean PT-HRSD +1 SD | -2.995 | 0.390 | -7.67 | <.0001 | |||||
| mean PT-HRSD -1 SD | -2.502 | 0.307 | -8.13 | <.0001 | |||||
|
| |||||||||
| SET (n=51) | 31.25 | 21.05 | 28.12 | 10.52 | mean PT-HRSD | -2.446 | 0.319 | -7.65 | <.0001 |
| mean PT-HRSD +1 SD | -2.345 | 0.548 | -4.28 | <.0001 | |||||
| mean PT-HRSD -1 SD | -2.548 | 0.276 | -9.23 | <.0001 | |||||
|
| |||||||||
| PBO (n=50) | 19.23 | 29.16 | 11.53 | 29.16 | mean PT-HRSD | -3.095 | 0.297 | -10.42 | <.0001 |
| mean PT-HRSD +1 SD | -4.120 | 0.486 | -8.47 | <.0001 | |||||
| mean PT-HRSD -1 SD | -2.071 | 0.298 | -6.93 | <.0001 | |||||
PT-HRSD = pre-treatment depression stability; SET = supportive-expressive therapy; MED = antidepressant medication; PBO = placebo; S.E. = Standard Error. Responders = percentage of patients who were considered responders at the end of treatment (i.e., HRSD score ≤9 or 50% HRSD score reduction and a HRSD score≤12); Remitters = percentage of patients who were considered remitters at the end of treatment (i.e., no longer meeting criteria for MDD and HRSD score <8).