Table 4.

DCA of PhoU A147 sorted by Direct Information

PhoR	PhoU	Mutual information	Direct Information	Distance (Å)
R148	A147	0.4267	0.0028	16.9
T195	A147	0.1738	0.0019	18.6
Y149	A147	0.5876	0.0016	9.3
L133	A147	0.2515	0.0016	20.9
I120	A147	0.1997	0.0015	20.0
E151	A147	0.4273	0.0014	8.0
L146	A147	0.3957	0.0014	15.8
L126	A147	0.2256	0.0014	22.2
V168	A147	0.3870	0.0014	15.0
F121	A147	0.2997	0.0013	22.1

Bolded PhoR residues are also in the top ten residues when sorted by Mutual Information