Table 5.

DCA of PhoU R148 sorted by Direct Information

PhoR	PhoU	Mutual information	Direct Information	Distance (Å)
R148	R148	0.4980	0.0045	11.4
I143	R148	0.2236	0.0019	11.2
L167	R148	0.2752	0.0017	5.4
P150	R148	0.3781	0.0017	11.6
L126	R148	0.1135	0.0016	14.5
E176	R148	0.3762	0.0014	13.5
I120	R148	0.2126	0.0013	15.2
F152	R148	0.2972	0.0012	13.4
N145	R148	0.4082	0.0011	12.9
G118	R148	0.4121	0.0011	16.3

Bolded PhoR residues are also in the top ten residues when sorted by Mutual Information