Table 1.
Proteins identified in SKBR3 and BT474 secretomes
| SKBR3 | BT474 | ||
|---|---|---|---|
| Protein Name | Symbol | Protein Name | Symbol |
| 14-3-3 protein epsilon | YWHAE‡ | 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 1 | PFKFB1 |
| 78 kDa glucose-regulated protein | HSPA5‡ | ||
| Actin, cytoplasmic 1 | ACTB‡ | 78 kDa glucose-regulated protein | HSPA5‡ |
| Alpha-enolase | ENO1‡ | Actin, cytoplasmic 1 | ACTB‡ |
| Aminoacylase-1 | ACY1‡ | ATP-dependent RNA helicase DDX3X | DDX3X‡ |
| Apolipoprotein A-I-binding protein | APOA1BP | Calreticulin | CALR‡ |
| Calreticulin | CALR‡ | Cellular retinoic acid-binding protein 2 | CRABP2‡ |
| Centrosomal protein of 63 kDa | CEP63 | Conserved oligomeric Golgi complex subunit 4 | COG4 |
| Ezrin | EZR‡ | ||
| Fructose-bisphosphate aldolase A | ALDOA‡ | Cutaneous T-cell lymphoma-associated antigen 8 | CTAGE8 |
| General transcription factor 3C polypeptide 5 | GTF3C5 | ||
| Fructose-bisphosphate aldolase A | ALDOA‡ | ||
| Glucose-6-phosphate 1-dehydrogenase | G6PD‡ | Gamma-glutamylcyclotransferase | GGCT‡ |
| Glutathione synthetase | GSS‡ | Glucose-6-phosphate isomerase | GPI‡ |
| Glyoxalase domain-containing protein 4 | GLOD4 | Glutathione synthetase | GSS‡ |
| Heat shock cognate 71 kDa protein | HSPA8‡ | Glyoxalase domain-containing protein 4 | GLOD4 |
| Heat shock protein HSP 90-alpha | HSP90AA1‡ | Heat shock cognate 71 kDa protein | HSPA8‡ |
| Hydroxymethylglutaryl-CoA synthase, cytoplasmic | HMGCS1 | Heat shock protein HSP 90-alpha | HSP90AA1‡ |
| Hydroxymethylglutaryl-CoA synthase, cytoplasmic | HMGCS1 | ||
| Isoform 2 of HLA class I histocompatibility antigen, Cw-16 alpha chain | HLA-C | ||
| Interleukin enhancer-binding factor 2 | ILF2 | ||
| Isoform MBP-1 of Alpha-enolase | ENO1‡ | Isoform 1 of Glutamate [NMDA] receptor subunit zeta-1 | GRIN1‡ |
| Lactoylglutathione lyase | GLO1‡ | ||
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 | DDAH2‡ | Mitochondrial intermediate peptidase | MIPEP |
| NADP-dependent malic enzyme | ME1 | ||
| Nucleoside diphosphate kinase A | NME1‡ | Neprilysin | MME‡ |
| Peroxiredoxin-1 | PRDX1‡ | Nucleoside diphosphate kinase A | NME1‡ |
| Peroxiredoxin-2 | PRDX2‡ | Nucleoside diphosphate kinase B | NME2‡ |
| Phosphatidylethanolamine-binding protein 1 | PEBP1‡ | Peroxiredoxin-2 | PRDX2‡ |
| Phosphatidylethanolamine-binding protein 1 | PEBP1‡ | ||
| Phosphoglycerate mutase 1 | PGAM1‡ | ||
| Proteasome activator complex subunit 1 | PSME1 | Phosphoglycerate mutase 1 | PGAM1‡ |
| Proteasome activator complex subunit 2 | PSME2‡ | Proteasome activator complex subunit 2 | PSME2‡ |
| Proteasome subunit alpha type-3 | PSMA3‡ | Proteasome subunit alpha type-3 | PSMA3‡ |
| Proteasome subunit alpha type-6 | PSMA6 | Proteasome subunit beta type-11 | PSMB11 |
| Proteasome subunit beta type-2 | PSMB2‡ | Proteasome subunit beta type-4 | PSMB4 |
| Proteasome subunit beta type-4 | PSMB4 | Proteasome subunit beta type-6 | PSMB6‡ |
| Purine nucleoside phosphorylase | PNP | Protein disulfide-isomerase A3 | PDIA3‡ |
| Putative ubiquitin-conjugating enzyme E2 N-like | UBE2NL | Purine nucleoside phosphorylase | PNP |
| Putative protein phosphatase inhibitor 2 | PPP1R2P3 | ||
| Rab GDP dissociation inhibitor beta | GDI2‡ | Rab GDP dissociation inhibitor beta | GDI2‡ |
| Serotransferrin | TF‡ | RAC-beta serine/threonine-protein kinase | AKT2 |
| Transferrin receptor protein 1 | TFRC‡ | Ras-related protein Rab-37 | RAB37 |
| Triosephosphate isomerase | TPI1‡ | RING finger and CHY zinc finger domain-containing protein 1 | RCHY1 |
| tRNA dimethylallyltransferase, mitochondrial | TRIT1 | ||
| Serpin B6 | SERPINB6‡ | ||
| Uncharacterized protein C6orf163 | C6ORF163 | Transitional endoplasmic reticulum ATPase | VCP‡ |
| Xaa-Pro dipeptidase | PEPD‡ | ||
| Triosephosphate isomerase | TPI1‡ | ||
| Tripartite motif-containing protein 35 | TRIM35 | ||
| Tropomyosin alpha-4 chain | TPM4 | ||
‡
indicates identified in exosomes.