Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2015 May 7.

Published in final edited form as: Neuropharmacology. 2010 Jan 6;58(7):972–980. doi: 10.1016/j.neuropharm.2009.12.017

Four hours after induction of thromboembolic stroke, rats were given saline (Cont), rtPA (6 mg/kg) alone or together with 18-aa-Tyr or 6-aa PAI-1 derive peptides (1 mg/kg each). Twenty four hours later, infarct volume (Panels 8A and 8B) and assessment of neurological function, expressed as the NSS (Panel 8C) were determined as described in Methods. The mean ± SEM of data from 12 animals/group is shown.

Four hours after induction of thromboembolic stroke, rats were given saline (Cont), rtPA (6 mg/kg) alone or together with 18-aa-Tyr or 6-aa PAI-1 derive peptides (1 mg/kg each). Twenty four hours later, infarct volume (Panels 8A and 8B) and assessment of neurological function, expressed as the NSS (Panel 8C) were determined as described in Methods. The mean ± SEM of data from 12 animals/group is shown.