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. Author manuscript; available in PMC: 2015 May 7.
Published in final edited form as: J Biol Rhythms. 2013 Jun;28(3):201–207. doi: 10.1177/0748730413490667

Figure 3.

Figure 3

The drug-induced change in Tb depends on the position of AGS in their circannual Tb cycle. Timing of drug administration indicated by vertical lines was identified as a trough (A) or a peak (B). C and D show CHA (0.1 mg/kg)–induced effects on Tb for AGS tested in a Tb trough (C) or a peak (D); arrows indicate time of drug administration. The drug-induced change in Tb was greater in animals tested during a trough than in animals tested during a peak (E). Data shown are mean ± SEM. *p < 0.05, n indicates the number of tests in a Tb peak or in a Tb trough.