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. Author manuscript; available in PMC: 2015 Aug 13.
Published in final edited form as: Science. 2015 Feb 13;347(6223):779–784. doi: 10.1126/science.aaa0314

Table 1.

Chemical structures and IC50 values of AI-10-49 and related compounds, determined by using the FRET assay.

Compound Name Compound Structure FRET IC50 (μM)
AI-4-88 graphic file with name nihms-684224-t0004.jpg >240
AI-4-57 graphic file with name nihms-684224-t0005.jpg 22 ± 8
AI-10-11 graphic file with name nihms-684224-t0006.jpg 14 ± 4
AI-10-19 graphic file with name nihms-684224-t0007.jpg >2.5
AI-4-83 graphic file with name nihms-684224-t0008.jpg 0.35 ± 0.05
AI-4-82 graphic file with name nihms-684224-t0009.jpg 0.44 ± 0.07
AI-4-71 graphic file with name nihms-684224-t0010.jpg 0.37 ± 0.07
AI-10-47 graphic file with name nihms-684224-t0011.jpg 2.0 ± 0.03
AI-10-49 graphic file with name nihms-684224-t0012.jpg 0.26 ± 0.01