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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2014 Sep 3;3(6):465–487. doi: 10.1002/wdev.152

Figure 2. Stages of nephrogenesis.

Figure 2

The adult metanephric kidney in mammals develops by a reciprocal interaction between the epithelial ureteric bud (blue) and the metanephric mesenchyme (purple). During the condensation stage, the loose mesenchymal cells of the MM condense around the tips of the epithelial UB. After the condensation stage, the induced mesenchyme undergoes a mesenchyme-to-epithelial conversion forms the comma and S-shaped structures. Later, the tubules elongate and the podocytes in the glomeruli fold to give rise to a mature nephron.