Table 1. Clinical and laboratory characteristics of the investigated groups.
| Parameter | Hypertension | Healthy |
|---|---|---|
| n (female/male) | 82 (54/28) | 34 (22/12) |
| Age [years] | 71.5 (19–94) | 62.5 (25–91) |
| Duration of the disease [years] | 6.5 (0.5–50) | N/A |
| SBP [mmHg] | 139.5 (108–165) | 120 (100–139) |
| DBP [mmHg] | 80 (60–105) | 76 (55–80)* |
| Number of patients with well controlled hypertension | 60 (73%) | N/A |
| CRP [mg/L] | 1.6 (0.1–13.94) | 0.9 (0.20–2.7)* |
| Creatinine [mg/dl] | 0.83 (0.59–1.65) | 0.78 (0.59–0.95) |
| GFR [ml/min/1,73m2] | 84.46 (39,57–149,17) | 96.15 (91–116.81)* |
| HbA1C [%] | 5.75 (4.73–6.62) | 5.60 (4.77–5.87) |
| Total serum protein [g/l] | 72 (65–88) | 73 (52–94) |
| TCh [mg/dl] | 214 (134–355) | 218 (176–273) |
| TG [mg/dl] | 107.5 (45–364) | 95 (51–252) |
| HDL [mg/dl] | 55 (26–93) | 58 (41–98) |
| LDL [mg/dl] | 135.5 (27–263) | 130 (105–195) |
| †Microalbuminuria (% of patients per group) | 58% | 0% |
| Weight [kg] | 70 (40–125) | 65 (40–100) |
| Hight [cm] | 164 (142–195) | 165 (152–186) |
| Waist circumference [cm] | 90 (60–130) | 85 (60–102) |
| BMI | 25.65 (17.52–37.87) | 23.7 (18.82–33.46)* |
| #Hypotensive drugs (% of treated individuals per group) | ACEI 40.9% | N/A |
| β-blocker 28.6% | ||
| Diuretic 26.1% | ||
| Ca-blocker 9.6% | ||
| Sartan 13.0% | ||
| Statins (% of treated individuals per group) | 12.1% | 14.7% |
As indicated by the distribution of the variables data are presented as medians with minimum and maximum values within parentheses; n = number of subjects, SBP = systolic blood pressure, DBP = diastolic blood pressure, GFR = glomerular filtration rate, HbA1c = glycated hemoglobin, TCh = total cholesterol, TG = triglycerides, LDL = low-density lipoprotein, HDL = high-density lipoprotein, N/A = non-applicable, ACEI = angiotensin-converting-enzyme inhibitor;
# hypertensive patients were on mono- or polytherapy, proportions of the patients treated with a particular group of drugs are presented as %;
† microalbuminuria was defined as >3 mg/dl in spot urine albumin specific-dipstick; statistically significant differences (p< 0.05) between the groups were marked with “*”.