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. 2015 May 7;10(5):e0125791. doi: 10.1371/journal.pone.0125791

Fig 4. Genes most frequently targeted by miRNAs, correlated to the presence of GBM or patient survival.

Fig 4

The presented genes are validated targets of miRNAs differentially expressed in the plasma samples of GPs and the members of the HIo subgroup and/or correlated to patient survival according to the results of analyses of this study, obtained by using the miRTarBase [32]. VEGFA—vascular endothelial growth factor A, HSPA1B—heat shock 70kDa protein 1B, ACTB—actin beta, HSP90AA1—heat shock protein 90kDa alpha (cytosolic), class A member 1, IGF1R—insulin-like growth factor 1 receptor, CCND1—cyclin D1, PTEN—phosphatase and tensin homolog, BCL2—B-cell CLL/lymphoma 2, CCNE1—cyclin E1, CDK4—cyclin-dependent kinase 4, PPIA—peptidylprolyl isomerase A (cyclophilin A), TUBA1B—tubulin, alpha 1b, WEE1—WEE1 G2 checkpoint kinase, CCND2—cyclin D2, CDK2—cyclin-dependent kinase 2, CDK6—cyclin-dependent kinase 6, BIRC5—baculoviral IAP repeat containing 5, EP300—E1A binding protein p300, RRM2—ribonucleotide reductase M2.