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. 2015 May 7;9(5):e0003764. doi: 10.1371/journal.pntd.0003764

Table 2. Incidence of CHIKV infections and seroprevalence of CHIKV PRNT in different age groups. a .

Age Subjects, n CHIKV PRNT ≥10, n (% of age group) b Symptomatic CHIKV infection, n [n/100 person-yrs (95% CI)] Subclinical CHIKV infection, n [n/100 person-yrs (95% CI)] Total CHIKV infection, n [n/100 person-yrs (95% CI)] Ratio of subclinical to symptomatic CHIKV infection
6 mos—5 yrs 148 1 (0.7) 5 [3.23 (1.23, 7.08)] 10 [6.46 (3.32, 11.47)] 15 [9.69 (5.66, 15.59)] 2:1
6–15 yrs 184 2 (1.1) 8 [4.23 (1.99, 7.98)] 24 [12.68 (8.33, 18.55)] 32 [16.91 (11.78, 23.56)] 3:1
16–30 yrs 168 34 (20.2) 2 [1.13 (0.23, 3.63)] 20 [11.32 (7.13, 17.14)] 22 [12.45 (8.02, 18.51)] 10:1
31–50 yrs 170 90 (52.9) 3 [1.8 (0.50, 4.81)] 21 [12.63 (8.05, 18.94)] 24 [14.43 (9.49, 21.12)] 7:1
>50 yrs 183 112 (61.2) 1 [0.55 (0.05, 2.59)] 12 [6.66 (3.64, 11.28)] 13 [7.21 (4.04, 11.98)] 12:1
All ages 853 239 (28.0) 19 [2.19 (1.36, 3.35)] 87 [10.03 (8.09, 12.31)] 106 [12.22 (10.06, 14.72)] 4.6:1

aBased on 853 subjects with both enrollment and 12-month blood collections.

bCHIKV PRNT titer at enrollment using 80% plaque reduction.

CHIKV = chikungunya virus; n = number; CI = confidence interval; PRNT = plaque reduction neutralization test.