Table 3. Incidence of CHIKV infections among individuals with negative baseline CHIKV PRNT in different age groups. a .
Age | Subjects with negative CHIKV PRNT b , n | Symptomatic CHIKV infection, n [n/100 person-yrs (95% CI)] | Subclinical CHIKV infection, n [n/100 person-yrs (95% CI)] | Total CHIKV infection, n [n/100 person-yrs (95% CI)] |
---|---|---|---|---|
6 mos—5 yrs | 147 | 5 [3.26 (1.23, 7.14)] | 10 [6.51 (3.34, 11.55)] | 15 [9.77 (5.71, 15.70)] |
6–15 yrs | 182 | 8 [4.27 (2.02, 8.06)] | 24 [12.82 (8.43, 18.76)] | 32 [17.09 (11.91, 23.82)] |
16–30 yrs | 134 | 2 [1.42 (0.28, 4.56)] | 20 [14.22 (8.96, 21.52)] | 22 [15.64 (10.08, 23.25)] |
31–50 yrs | 80 | 3 [3.81 (1.06, 10.18)] | 21 [26.70 (17.02, 40.04)] | 24 [30.51 (20.05, 44.64)] |
>50 yrs | 71 | 1 [1.41 (0.13, 6.60)] | 12 [16.98 (9.27, 28.75)] | 13 [18.39 (10.30, 30.55)] |
All ages | 614 | 19 [3.01 (1.87, 4.61)] | 87 [13.79 (11.12, 16.92)] | 106 [16.80 (13.83, 20.24)] |
aBased on 614 subjects with both enrollment and 12-month blood collections who had negative baseline CHIKV PRNT titer.
bCHIKV PRNT titer at enrollment using 80% plaque reduction.
CHIKV = chikungunya virus; n = number; CI = confidence interval; PRNT = plaque reduction neutralization test.