Table 2. Effect of genetically predicted testosterone on markers of systemic inflammation among 4182 and a subgroup of 1636 men (50+) in a Mendelian randomization study design, Guangzhou Biobank Cohort Study, 2003–2008.
| Outcome | n | Beta coefficient a | 95% CI |
|---|---|---|---|
| WBC Count | 4180 | -0.01 | -0.05 to 0.04 |
| (109/L) | |||
| Granulocyte | 4167 | -0.02 | -0.06 to 0.02 |
| (109/L) | |||
| Lymphocyte | 4182 | 0.005 | -0.01 to 0.02 |
| (109/L) | |||
| hsCRP (mg/L) | 1636 | -0.05 | -0.15 to 0.06 |
aBeta coefficient refers to the average change in white blood cell and its differentials counts and hsCRP level with each unit (nmol/L) increase in genetically predicted testosterone.