Description of communication between flesh and rind. A, Network-Mrf. The Spearman correlation coefficient was calculated for each metabolite between the rind and the flesh in four varieties. Significant correlations (Spearman correlation > 0.75) supported by multiple varieties are represented. The black lines represent correlations occurring in four varieties, and the gray lines represent correlations occurring in three varieties. B, Genome-wide scale comparison of copy numbers of transporter genes between citrus and other model fruits. Genome-wide statistics show copy numbers of all orthologous genes annotated to transporters in 18 genomes of fruit species (genome data were downloaded from the databases listed in Supplemental Table S6). C, List of up-regulated transporter genes in the rind and the flesh. Transporter genes that were up-regulated in the rind or the flesh are marked in black. AAP2, AMINO ACID PERMEASE2; ABC-2, ABC2-TYPE TRANSPORTER FAMILY PROTEIN; BAT1, BIDIRECTIONAL AMINO ACID TRANSPORTER1; CAT5, CATIONIC AMINO ACID TRANSPORTER5; INT1, INOSITOL TRANSPORTER1; LAX2, LIKE AUXIN RESISTANT2; LHT1, LYSINE HISTIDINE TRANSPORTER1; MATE, MULTIDRUG AND TOXIC-COMPOUND EXTRUSION EFFLUX FAMILY PROTEIN; MFS, MAJOR FACILITATOR SUPERFAMILY PROTEIN; MRP3, MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN3; NIP1;2, NOD26-LIKE INTRINSIC PROTEIN1;2; Nodulin MtN3, NODULIN MtN3 FAMILY PROTEIN; NRT1:2, NITRATE TRANSPORTER1:2; PDR6, PLEIOTROPIC DRUG RESISTANCE6; PGP9, P-GLYCOPROTEIN9; PIP2;2, PLASMA MEMBRANE INTRINSIC PROTEIN2;2; PUP1, PURINE PERMEASE1; SAG29, SENESCENCE-ASSOCIATED GENE29; STP1, SUGAR TRANSPORTER1; SUC1, SUCROSE-PROTON SYMPORTER1; TaaT, TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN; TIP3;1, TONOPLAST INTRINSIC PROTEIN3;1; UTR3, UDP-GAL TRANSPORTER3.