Table 1.
Patient and disease characteristics
| Characteristic | No. of Patients (%) |
|---|---|
| Sex | |
| Female | 41 (19) |
| Male | 180 (81) |
| Ethnicity | |
| Asian/Pacific Islander | 1 (0.5) |
| Black/African-American | 44 (20) |
| Hispanic/Latino | 38 (17) |
| Other/unspecified | 2 (1) |
| White | 136 (61.5) |
| Initial Disease Site | |
| Glottic | 43 (19) |
| Subglottic | 3 (1) |
| Supraglottic | 125 (57) |
| Transglottic | 50 (23) |
| Nodal Status | |
| N+ | |
| N1 | 41 (19) |
| N2A | 6 (3) |
| N2B | 42 (19) |
| N2C | 39 (18) |
| N3 | 16 (7) |
| NX | 3 (1) |
| N0 | |
| N0 | 74 (33) |
| Smoking History at Diagnosis | |
| None | 8 (4) |
| Unknown or unspecified | 5 (2) |
| Positive | 208 (94) |
| History of GERD at Presentation | |
| Yes | 50 (23) |
| No | 89 (40) |
| Unknown or unspecified | 82 (37) |
| Dysphagia at Presentation | |
| None | 90 (41) |
| Unknown or unspecified | 20 (9) |
| Positive | 111 (50) |
| Vocal Cord Impairment at Presentation | |
| Impairment | 88 (40) |
| Paralysis | 73 (33) |
| Unknown or unspecified | 28 (13) |
| None | 32 (14) |
| Pathologic Grade* | |
| Moderately differentiated | 124 (56) |
| Poorly differentiated | 57 (26) |
| Unknown/unspecified | 24 (11) |
| Well differentiated | 16 (7) |
| Lymphovascular Space Invasion* | |
| None | 50 (23) |
| Unknown or unspecified | 133 (60) |
| Positive | 38 (17) |
| Perineural Invasion* | |
| None | 80 (36) |
| Unknown or unspecified | 102 (46) |
| Positive | 39 (18) |
| Vascular invasion* | |
| None | 71 (32) |
| Unknown or unspecified | 123 (56) |
| Positive | 27 (12) |
| Extracapsular nodal extension*§ | |
| None | 64 (29) |
| Unknown or unspecified | 100 (45) |
| Positive | 57 (26) |
| Subglottic extension*§ | |
| None | 87 (39) |
| Unknown or unspecified | 38 (17) |
| Positive | 96 (43) |
| Paraglottic space involvement*§ | |
| None | 54 (24) |
| Unknown or unspecified | 102 (46) |
| Positive | 65 (29) |
| Pre-epiglottic space involvement*§ | |
| None | 40 (18) |
| Unknown or unspecified | 84 (38) |
| Positive | 97 (44) |
| Hypopharyngeal involvement*§ | |
| Pyriform sinus | 62 (28) |
| Hypopharynx NOS | 15 (7) |
| None | 101 (46) |
| Post-cricoid involvement | 5 (2) |
| Posterior hypopharynx NOS | 5 (2) |
| Unknown or unspecified | 33 (15) |
| Cartilage invasion*§ | |
| Full thickness or greater erosion | 102 (46) |
| Minor/inner cortex erosion | 43 (19.5) |
| None | 50 (22.5) |
| Unknown or unspecified | 26 (12) |
*
Information obtained from pathology reports (for patients who had surgery)
§
Information obtained from medical records (pathology, imaging, or clinical reports)
Abbreviations: GERD, gastroesophageal reflux disease; NOS, not otherwise specified.