Table 1.

Characteristics of 108 neonates with seizures due to hypoxic-ischemic encephalopathy after and before implementation of a Neonatal Neurocritical Care Service.

	Post- Neonatal Neurocritical Care Service Era (n=55)	Pre- Neonatal Neurocritical Care Service Era (n=53)	p-value
Male sex	27(49)	35(66)	0.08
Gestational age, weeks	39.6 ± 1.4	39.7 ± 1.5	0.8
Cesarean section	31(56)	27(51)	0.6
10-minute Apgar score	4(3 to 5)	6(4 to 7)	0.001
Base Excess*	−18 ± 7	−18 ± 7	0.6
Encephalopathy Severity			0.03
-Moderate	32(58)	41(77)
-Severe	23(42)	12(23)
Therapeutic hypothermia	52 (95%)	4 (8%)	<0.001
Seizure Burden**			0.4
-Few Seizures (<5)	30(55)	36(68)
-Many Seizures (>5)	19(35)	13(25)
Status Epilepticus	6(11)	4(8)
Length of stay, days	8(6 to 11)	13(6 to 19)	0.01
Death before hospital discharge	16(29)	11(21)	0.3

Values are given in terms of n (%), mean ± standard deviation, or median (25th percentile to 75th percentile).

^*Values based on worst base excess from cord gas or first blood gas.

^**Seizure based on chart documentation of clinical events that were suspicious for seizure(s) or on electroencephalogram (EEG) confirmed seizures.