Table 5.
Microscopic features of this clinical series
Microscopic characteristic | Number (n = 67) |
---|---|
Bosselated or lobulated | 51 |
Multifocal | 9 |
Cystic | 62 |
Beading | 67 |
Tubules | 67 |
Luminal squamous ball/morule | 41 |
Stromal sclerosis or collagen present | 42 |
Myxoid stroma | 64 |
Histiocytes | |
Lipofucsin/hemosiderin laden, luminal location | 20 |
Lipofucsin/hemosiderin laden, stromal location | 11 |
Foamy, luminal and/or stromal location | 11 |
Luminal hemorrhage | 51 |
Microliths (calcifications; psammoma bodies) | 33 |
Necrosis present | 0 |
Mitotic figures | |
Present (number of cases) | 24 |
Mean (per 10 HPFs) | 0.5 |
Range (per 10 HPFs) | 1–4 |
Atypical figures identified | 0 |
Other features | |
Degenerated or infarcted | 3 |
Tyrosine crystals | 1 |
Oncocytic | 2 |
Mucinous metaplasia | 1 |
Surgical margin status | |
Positive | 28 |
Negative | 39 |
Number of slides examined (mean) | 1.2 |
Difference in features between surgical sample and TMA core | None |
HPF high power field, TMA tumor microarray