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Effect of lactadherin-derived peptides on cell viability and Wa rotavirus infectivity in Caco-2 cells
| Peptides | Features | IC50 | 95% confidence interval | CC50 | SI |
|---|---|---|---|---|---|
| μm | μm | ||||
| pDGE-RGD | Wild type peptide | 8.8 | 6.1–12.5 | 945.1 | 102.7 |
| pDGE-RGE | aa substitution in position 16 | 46.0 | 24.9–84.9 | >880 | 19.1 |
| pAGE-RGD | aa substitution in position 3 | 101.7 | 78.6–131.6 | >880 | 8.7 |
| pAGE-RGE | aa substitutions in position 3 and 16 | 152.5 | 123.3–188.6 | >880 | 5.8 |
