Fig. 3.

Strengths of detected interferences. A, frequencies of intralibrary and score-based strategy-detected fragment ion interferences of the indicated strengths (fraction of observed XIC) in human urine background sample peak groups filtered at an estimated 1% FDR. B, accuracy of reported strengths of interferences of M. tuberculosis precursor ions by human urine peptides in the control data set samples. Reported interference strengths are plotted against their true values as computed based on the XIC of corresponding peak groups lacking the interference in the neat background samples.