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. 2015 Mar 26;125(19):3024–3031. doi: 10.1182/blood-2015-01-623991

Table 2.

Risk-stratified outcomes after NMA haplo BMT based on refined DRI

Variable: refined DRI group Probability (95% CI) P*
All patients (n = 372) Low risk (n = 71) Intermediate risk (n = 241) High/very high risk (n = 60)
NRM (CuI) .60
 Day 180 0.08 (0.05-0.11) 0.03 (0-0.07) 0.10 (0.06-0.14) 0.05 (0-0.11)
 1 y 0.11 (0.08-0.14) 0.10 (0.03-0.17) 0.13 (0.08-0.17) 0.05 (0-0.11)
Relapse (CuI) <.0001
 1 y 0.37 (0.32-0.42) 0.17 (0.08-0.26) 0.38 (0.32-0.44) 0.58 (0.46-0.71)
 3 y 0.46 (0.41-0.51) 0.20 (0.11-0.30) 0.48 (0.41-0.54) 0.67 (0.55-0.80)
PFS <.0001
 1 y 0.52 (0.47-0.57) 0.73 (0.63-0.84) 0.50 (0.44-0.56) 0.37 (0.26-0.51)
 3 y 0.40 (0.35-0.45) 0.65 (0.55-0.78) 0.37 (0.31-0.44) 0.22 (0.14-0.36)
DFS <.0001
 1 y 0.51 (0.46-0.57) 0.70 (0.60-0.82) 0.50 (0.44-0.56) 0.35 (0.25-0.49)
 3 y 0.61 (0.57-0.66) 0.64 (0.54-0.76) 0.37 (0.31-0.44) 0.22 (0.14-0.36)
OS .0001
 1 y 0.68 (0.63-0.73) 0.81 (0.73-0.91) 0.67 (0.61-0.73) 0.55 (0.44-0.69)
 3 y 0.50 (0.45-0.56) 0.71 (0.60-0.82) 0.48 (0.42-0.55) 0.35 (0.24-0.49)

DFS, disease-free survival.

*

P for differences between refined DRI risk groups, with stratification by BMT year.