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. 2015 Mar 31;19(1):11–18. doi: 10.5717/jenb.2015.19.1.11

Fig. 1.

Fig. 1.

NGF, BDNF, and synapsin I protein levels in hippocampal dentate gyrus following treadmill exercise after social isolation. (A) NGF, (B) BDNF, and (C) synapsin I. NGF, BDNF, and synapsin I protein level were significantly decreased in the ICG as compared to the GCG, and these levels were significantly improved in the IEG. GCG: group housing and control group, n = 10; GEG: group housing and exercise group, n = 10; ICG: isolated housing and control group, n = 10; IEG: isolated housing and exercise group, n = 10 (respectively 5 rats for immunohistochemistry, 5 rats for western blotting). Significant difference among groups at p < 0.001. Different letters represent significant variations calculated by 1-way analysis of variance (ANOVA) and the LSD test.