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. 2015 Apr 29;15:324. doi: 10.1186/s12885-015-1315-9

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© Ito et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of DHMEQ in combination with paclitaxel on tumor growth in T24PR mouse xenograft model. T24PR cells (2 × 10⁶ cells) were implanted in the flank of athymic nude mice. Seven days after implantation, daily intraperitoneal administration of 2 mg/kg of DHMEQ was started. Paclitaxel (10 mg/kg) was administered intraperitoneally on day 14 and day 21 after cancer cell implantation. The tumor volume of each animal was monitored and compared with that in the vehicle-treated control group or paclitaxel-treated group. : *< 0.05, **< 0.01 compared with another group. Each value represents the mean ± SE.