Table 2.
Number of patient years with events and use of renal replacement therapy by baseline CKD stage
| Baseline CKD stage 1 | Overall | ||||
|---|---|---|---|---|---|
| CKD 1-3B 2 | CKD 4 | CKD 5 not on dialysis | On dialysis | ||
| Number of patients | 1,494 | 2,228 | 1,017 | 2,498 | 7,246 |
| Vascular death | 36 (0.6%) | 92 (1.0%) | 86 (2.2%) | 235 (2.5%) | 449 (1.6%) |
| Non-vascular death | 97 (1.6%) | 219 (2.5%) | 151 (3.8%) | 453 (4.9%) | 920 (3.3%) |
| Non-fatal major vascular event in the current annual period | 93 (1.5%) | 222 (2.5%) | 128 (3.2%) | 385 (4.1%) | 828 (2.9%) |
| Kidney transplantation in the current annual period | 14 (0.2%) | 142 (1.6%) | 213 (5.4%) | 625 (6.7%) | 994 (3.5%) |
| On functioning kidney transplant from an earlier annual period | 9 (0.1%) | 126 (1.4%) | 335 (8.5%) | 1,170 (12.5%) | 1,663 (5.9%) |
| Dialysis initiated during the current annual period | 77 (1.3%) | 548 (6.2%) | 718 (18.2%) | 18 (0.2%) | 1,362 (4.8%) |
| On dialysis since an earlier annual period | 44 (0.7%) | 609 (6.9%) | 1,337 (33.8%) | 7,526 (80.6%) | 9,516 (33.7%) |
Data are the number of annual periods in which the defined event occurs or the RRT status, and percentage of all annual periods. In each annual period, each participant on renal replacement therapy is classified into one of: (1) kidney transplantation in current annual period; (2) functioning kidney transplantation from an earlier annual period; (3) dialysis initiated during the current annual period; and (4) on dialysis since an earlier annual period.
CKD = chronic kidney disease.
19 patients who received a transplant prior to randomization were excluded from the tabulation by baseline CKD stage.
2Predominantly CKD stage 3B (eGFR ≥30 to <45 ml/min/1.73m2).